*** SCHEDULE & PROGRAM ***

(updated on October 9, 2009)

Please note that this program may be updated at any time by the organizers
You are suggested to prepare your lecture ppt under the version of software 'Office 2003' or 'Office 2007'

Sunday, October 18, 2009

16:00-19:00  Registration and Poster setup

19:00-19:15  Summary of Conference Preparation - Jianhua Wang (Beijing, P. R. China)

19:30-21:30  Welcome Evening Buffet

Monday, October 19, 2009

08:50-09:10  Student Award Ceremony / Opening Remarks
                     Members of International Scientific Committee and Local Organizing Committee of 9th ILC

Session I - Lactoferrin structure-function relationships
                           Chair Persons: J. H. Wang - D. Legrand

09:10-09:40  Edward N. Baker (Auckland,New Zealand)
                     Focusing a high-resolution lens on the structure of lactoferrin

09:40-10:00   Hardiville Stephan (Villeneuve d’Ascq cedex, France)
                     The O-GlcNAc/phosphate interplay regulates both delta-lactoferrin stability and transcriptional activity

10:00-10:20   Benjamin Ashby (Sydney, Australia)
                     Structural modifications to bovine lactoferrin and their effects on promotion of corneal epithelial wound healing in vitro

10:20–10:40   Masaru Tanokura (Tokyo, Japan)
                     Studies of the structure of multiferric ion-bound lactoferrin: a new antianemic edible material

10:40-11:20   Coffee Break-Posters

  Poster

Pan Fenggang (Tokyo, Japan)
Studies of the structure of multiferric ion-bound lactoferrin: a new antianemic edible material

Session II - Lactoferrin ligands / receptors
                             Chair Persons: E. N. Baker – S. Y. Choi

11:20-11:50    Bo Lonnerdal (Davis, CA, USA)
                     Lactoferrin receptor mediates cellular activities of lactoferrin

11:50-12:20   Annick Pierce (Villeneuve d’Ascq, France)
                     Human delta-lactoferrin is a transcription factor which regulates cell survival

12:20-12:40   Frank Mao (Taichung, Taiwan, China)
                     Chromium-Lactoferrin complex supplementation ameliorates nonalcoholic fatty liver disease in mice

12:40-13:00   Zhihong Liu (Calgary, Alberta, Canada)
                     Interactions between lactoferrin and regulatory calcium binding proteins

13:10-15:00    Lunch Time

Session III - Regulation of cell proliferation and differentiation by lactoferrin
                                Chair Persons: C. Teng – H. Vogel

15:00-15:30   Sang-Yun Choi (Seoul, Korea South)
                     Cell stress-responsive lactoferrin in growth control signaling

15:30-15:50   Yoshiharu Takayama (Tsukuba Ibaraki, Japan)
                     Regulation of osteogenic and chondrogenic differentiation by lactoferrin

15:50-16:10   Mattias Münnich (Goteborg, Sweden)
                     A novel polypeptide derived from human lactoferrin prevents post-surgical adhesion formation

16:10-16:30   Hongrui Jiang (Harbin, P. R. China)
                     Structure-function relationship of synthetic peptides homologous to a loop structure on bovine lactoferricin apoptosis in jurkat cells

16:30-17:10   Coffee Break-Posters
  Posters

Anthony Schryvers (Calgary, Alberta, Canada)
Structural and functional features of lactoferrin binding B from Gram-negative pathogens

Hong Tian (Auckland, New Zealand )
Evaluation of the cytoprotective effects of bovine bactoferrin against intestinal toxins using cellular model systems

Tienan Zhang (Harbin, P. R. China)
Structure-function relationship of synthetic peptides homologous to a loop structure on bovine lactoferricin apoptosis in jurkat cells

Session IV - Immunomodulating effects of lactoferrin
                              Chair Persons: J. Cornish – G. X. Cheng

17:10-17:40   Jillian Cornish (Auckland, New Zealand)
                     Lactoferrin as an effecter molecule in the skeleton

17:40-18:00   Dominique Legrand (Villeneuve d'Ascq cedex, France)
                     A review of the roles of lactoferrin in immunity

18:00-18:20   Anne van der Does (Leiden, The Netherlands)
                     Modulation of the immune system by the lactoferrin-derived peptide hLF1-11

18:20-18:40  Satoru Morishita (Tokyo, Japan)
                     Potent anti-adipogenic action of enteric-coated lactoferrin: alteration of gene expression profiles of pre-adipocyte derived from rat mesenteric fat by lactoferrin

  Posters

Yu Kataoka (Tokyo, Japan)
Original ointment mixed with lactoferrin having anti-inflammatory activity in vivo

Esthelle Hoedt (Villeneuve d'Ascq, France)
The use of TaqMan real time PCR to discriminate and evaluate the variation in lactoferrin and delta-lactoferrin expression levels

Sandra Gessani (Rome, Italy)
Immunomodulatory effects of lactoferrin in antigen presenting cells

19:00-21:45  Reception Dinner of New Baili
         19:10-19:40    Going to the Bianyifang Anhua Duck Restaurant by the conference bus.
         19:45-21:45    Reception Dinner of New Baili (NBL)
         21:45-22:30   Getting on the conference bus and return to Beijing Friendship Hotel

Tuesday, October 20, 2009


Session V - Lactoferrin in pathologies
                            Chair Persons: A. Pierce – H. Tsuda

09:00-09:30   Piera Valenti ( Rome, Italy)
                      Lactoferrin in curing hypoferremia and anaemia: mechanism of action

09:30-09:50   Arnaud Malet (France)
                      Bovine Lactoferrin improves bone status of ovariectomized mice via immune function modulation

09:50-10:10    Fabiana Superti (Rome, Italy)
                      Lactoferrin treatment inhibits influenza virus infection in vitro

10:20-11:00    Coffee Break-Posters

  Posters

Hong Tian (Auckland, New Zealand)
Influence of bovine lactoferrin on selected probiotic bacteria and intestinal pathogens

Inger Mattsby-Baltzer (Bucharest, Romania)
Anti-tumor capacity of liposome-entrapped lactoferrin: basic research and future opportunities

Magda Marchetti (Rome, Italy)
Bovine lactoferrin interacts with cable pili of Burkholderia cenocepacia

Nidia Leon-Sicairos (Sinaloa, México)
Vesicular traffic of human holo-transferrin and holo-lactoferrin in Entamoeba histolytica

Nidia Leon-Sicairos (Sinaloa, México)
Effect of bovine lactoferrin in a murine model of intestinal amoebiasis

Piera Valenti (Rome, Italy)
Lactoferrin modulates gene expression of cystic fibrosis bronchial cells invaded by iron and zinc-modulated biofilm of Burkholderia cenocepacia clinical isolates

 

Session V - Lactoferrin in pathologies (continued)
                            Chair Persons: A. Pierce – H. Tsuda

11:00-11:30    Hans Vogel (Calgary, Alberta, Canada)
                     Lactoferrin and its interactions with other immuno-modulating, biofluid proteins such as osteopontin

11:30-11:50    Anne Blais (Paris, France)
                     Bovine lactoferrin ingestion protects bone microarchitecture in ovariectomized mice

Session VI - Antimicrobial activity of lactoferrin and lactoferrin-derived protein (peptide)
                              Chair Persons: A. Schryvers – J. H. Wang

11:50-12:20    Anthony Schryvers (Calgary, Alberta, Canada)
                      Structural and functional features of lactoferrin binding B from Gram-negative pathogens

12:20-12:40    Xuejing Bai (Beijing, P. R. China)
                      Molecular design, expression and characterization of recombinant bovine lactoferrin-derived antimicrobial protein

12:40-13:00    Susan Mosquito Guillen (Lima, Perú)
                      Effect of the bovine lactoferrin in Salmonella ser. Typhimurium infection in mice

13:10-15:00    Lunch Time

Session VI - Antimicrobial activity of lactoferrin and lactoferrin-derived protein (peptide) (continued)
                              Chair Persons: P. Valenti – K. Shimazaki

15:00-15:30    Nidia Leon-Sicairos (Sinaloa, México)
                      Bactericidal activity of bovine lactoferrin and LFchimera against antibiotic-resistant Staphylococcus aureus and Escherichia coli

15:30-15:50    Hiroyuki Wakabayashi (Zama Kanagawa, Japan)
                      Lactoferrin inhibits biofilm and dental plaque of periodontopathic bacteria

15:50-16:10    Yifan Liu (Hangzhou, P. R. China)
                      Comparative antimicrobial activity in vitro and mechanism of synthetic peptides derived from bovine lactoferricin

16:10-16:40    Coffee Break-Posters

  Posters

Elena Sadchikova (Moscow, Russia)
Recombinant human lactoferrin dominates antibiotics resistant microorganisms

Mai Murata (Zama-City, Japan)
Influence of lipopolysaccharides on the antimicrobial activity of lactoferrin against Escherichia coli

Nidia Leon-Sicairos (Sinaloa, México)
Bactericidal activity of bovine lactoferrin and LFchimera against antibiotic-resistant Staphylococcus aureus and Escherichia coli

Nidia Leon-Sicairos (Sinaloa, México)
Microbicidal effect of the bovine lactoferrin peptides Lactoferricin, Lactoferrampin and the LFchimera on the parasite Entamoeba histolytica

Shaojiang Chen (Hokitika, New Zealand)
Low iron bovine lactoferrin with improved antimicrobial activity

Sakawrat Kanthawong (Khon Kaen, Thailand)
LFchimera, consisting of both antimicrobial lactoferrin domains, is a potent bactericidal agent to combat Burkholderia pseudomallei

 

Session VII - Molecular design and expression of lactoferrin-derived protein (peptide)
                                 Chair Persons: A. Schryvers – D. Legrand

16:40-17:10    Yalin Yang (Beijing, P. R. China)
                      Design and expression of lactoferrin-derived peptide

17:10-17:30    Xingjun Feng (Harbin, P. R. China)
                      Designing, synthesis and antibacterial activity of an antimicrobial peptide LFB15-ME8

17:30-17:50    Yonggang Xie (Hangzhou, P. R. China)
                      Antibacterial and hemolytic activities of lactoferricin, palustrin-OG1 and cecropin A: a comparative study

17:50-18:40    Dinner time

18:45-22:30   Self-paid Opera (to buy ticket by currency RMB when signing in)
         18:45-19:30    Going to the National Centre for the Performing Arts by the conference bus.
         19:30-21:30   The Butterfly Lovers - Modern ‘Yue Opera’ (A, Ancient love story, ’Song’ dynasty 352-373AD; B, the ‘Yue opera’ from a Yue State of eastern China, 475-221BC)
         21:45-22:30   Getting on the conference bus and return to Beijing Friendship Hotel

Wednesday, October 21, 2009


Session VII - Molecular design and expression of lactoferrin-derived protein (peptide) (continued)
                                 Chair Persons: A. Schryvers – D. Legrand

09:00-09:30   Christina Teng (Raleigh, USA)
                      Lactoferrin: The path from gene to protein

09:30-09:50   Zhiru Tang (Changsha, P. R. China)
                      High level fusion expression of bovine lactoferricin and lactoferrampin genes in Photorhabdus luminescens TZR001

09:50-10:10    Frans de Loos (Leiden, The Netherlands)
                      Stability and safety of production of recombinant human lactoferrin in transgenic cows — A report on 20 years of experience

10:10-10:30    Coffee Break-Posters

  Posters

Fu Fan (Hangzhou, P. R. China)
Expression and purification the antimicrobial peptide protegrin-1 in E. coli

Xuejing Bai (Beijing, P. R. China)
Molecular design, expression and characterization of recombinant bovine lactoferrin-derived antimicrobial protein

Yalin Yang (Beijing, P. R. China)
Expression of a candidacidal peptide lactoferrampin in Escherichia coli

Zigang Tian (Beijing, P. R. China)
Design and Expression of antimicrobial hybrid peptides from LFB15(W4,10), HP(2-20), and cecropin A

Zigang Tian (Beijing, P. R. China)
Cloning, expression and characterization of Kunming mice lactoferrin and its N-lobe

 

Session VIII - Recombinant and transgenic lactoferrins
                                   Chair Persons: B. Lonnerdal – A. Pierce

10:30-11:00    Guoxiang Cheng (Shanghai, P. R. China)
                     Biosafety assessment of human lactoferrin transgenic goat

11:00-11:20    Zigang Tian (Beijing, P. R. China)
                     Cloning, expression and characterization of Kunming mice lactoferrin and its N-lobe

11:20-11:40    Ning Huang (Davis California, USA)
                     Recombinant human lactoferrin production and its application in the management of diarrhea

11:45-12:45    Lunch Time

14:00-18:00   Sponsors meeting - Coordinated by G. X. Cheng, L. Pierson,J.-P. Perraudin, H. Matsumura

12:45-19:30   Self-paid tourism (to buy ticket by currency RMB when signing in)
         12:45-13:30    Getting on the conference bus to the Palace Museum at the centre of Beijing
         13:30-18:00    Tourism
         18:30-19:30    Getting on the conference bus and return to the Beijing Friendship Hotel
         19:30-21:30    Gala dinner (your formal or business casual dress would be advised)

Thursday, October 22, 2009


Session VIII - Recombinant and transgenic lactoferrins (continued)
                                   Chair Persons: B. Lonnerdal – G. X. Cheng

09:00-09:30   Ning Li (Beijing, P. R. China)
                      Production of functional recombinant human lactoferrin in the milk of transgenic cloned cattle

09:30-09:50   Huiqin Yu (Shanghai, P. R. China)
                      Dominant expression of functional human lactoferrin in transgenic goats

  Posters

Aliaksandr Budzevich (Zhodino, Minsk region, Belarus)
Human lactoferrin transgenic goat breeding

Hsiao-Ling Chen (Changhwa, Taiwan, China)
Recombinant porcine lactoferrin expressed in the milk of transgenic mice enhances offspring growth performance

Igor Goldman (Moscow, Russia)
Recombinant human lactoferrin in the milk of transgenic animals

Tian Yu (Beijing, P. R. China)
Comparative analysis of the site-specific N-glycosylation of hLF and rhLF expressed in transgenic cloned cattle

Xuejing Bai (Beijing, P. R. China)
Bovine lactoferrin and its N-lobe produced in recombinant Pichia pastoris demonstrate differences in iron binding and antimicrobial activities

Zhiru Tang (Changsha, P. R. China)
The expression of mutated bovine lactoferricin gene in Escherichia coli YZ2005 and its antimicrobial activity identification

 

Session IX - Lactoferrins applications
                              Chair Persons: N. Li – J.-P. Perraudin

09:50-10:20   Kei-ichi Shimazaki (Sapporo, Hokkaido, Japan)
                      Preliminary approach to overview lactoferrin's multifunctional fields by text mining method

10:20-10:50   Jean-Paul Perraudin (Tubize, Belgium)
                      Reduction of the biological activities of the lactoferrin by the presence of the endotoxins on its molecular structure

10:50-11:20     Coffee Break – Posters

  Posters

Atsushi Ishikado (Takatsuki, Japan)
Human trial of liposomal lactoferrin supplementation for periodontal disease

Chuan-Mu Chen (Taichuang, Taiwan, China)
Lactoferrin as a natural regimen of selective decontamination of the digestive tract

Kei-ichi SHIMAZAKI (Tokyo, Japan)
Information extraction for an overview of lactoferrin multi-functionality by a text mining method

Theresa Ochoa (Lima, Peru)
Implementation of a community-based clinical trial of lactoferrin for prevention of diarrhea in children

Jean-Paul Perraudin (Tubize, Belgium)
Hypothiocyanite and Lactoferrin use for the treatment of Pseudomonas aeruginosa, Burkholderia cepacia and MRSA in cystic fibrosis and respiratory diseases

Jeremy H. Brock (Glasgow, UK) An overview of functions of lactoferrin with medical and nutraceutical applications

 

Session IX - Lactoferrins applications (continued)
                              Chair Persons: J.-P. Perraudin – N. Li

11:10-11:40    Hiroyuki Tsuda (Nagoya, Japan)
                    Suppressive effect of orally administered bovine lactoferrin on the growth of colorectal polyps in a randomized, placebo-controlled clinical trial

11:40-12:10    Theresa Ochoa (Lima, Peru)
                     Implementation of a community-based clinical trial of lactoferrin for prevention of diarrhea in children

12:10-12:30    Pilar Mier (Cantabria, Spain)
                     Optimizing the production of high-added value proteins through Hi-tech separation technologies

12:30-12:50   Koji Yamauchi (Kanagawa, Japan)
                     Applications of bovine lactoferrin and bovine lactoferrin hydrolyzate

12:50-13:05   Genevieve Spik Award Ceremony — Bo Lonnerdal (Davis, CA, USA)

13:05-13:20   Concluding remarks — Annick Pierce (Villeneuve d’Ascq, France)

13:20-14:45   Lunch time

Session X - Open Round Table Meeting
                            Chair Persons: B. Lonnerdal – J. H. Wang

15:00-18:00   A discussion on perspective of cooperation & coordination for lactoferrin R & D

18:30-20:30   Buffet dinner

More detail information on tourism can be seen from the following websites:
The Palace museum, the Great Wall in Beijing and other popular tourist destinations out of Beijing are detailed in the following websites:
http://www.muztagh.com/beijing/
http://www.travel-images.com/china.html
http://www.travelchinaguide.com/