*** SCHEDULE & PROGRAM ***

( updated on September 4 ^th, 2007 )

Please note that this program may be changed at any time by the organizers.

4:00-7:00 pm   Registration and Poster setup

7:00-7:30 pm   Opening Remarks - Annick Pierce, Piera Valenti & Dominique Legrand

7:30-9:30 pm   Welcome Evening Buffet

Chair Persons : J. Mazurier – H. Vogel

9:00-9:30 am   Edward N. Baker (Auckland, New Zealand)

"A structural overview of lactoferrin function - twenty years on"

9:30-9:50 am   Celia Conesa (Zaragoza, Spain)

"Investigation of the interaction of human lactoferrin with human ceruloplasmin"

9:50-10:10 am   Vadim Vasilyev (Saint-Petersburg, Russia)

"Complexes of ceruloplasmin with lactoferrin and myeloperoxidase as an index of neutrophil activity"

Chair Persons : E. Baker – B. Lönnerdal

10:40-11:10 am  Christina Teng (Research Triangle Park, NC, USA)

"Mechanism of LPS induction on lactoferrin expression in mammary gland cells"

11:10-11:30 am  Antonella Baldi (Milan, Italy)

"Effect of lipopolysaccharides on bovine lactoferrin mRNA expression by mammary epithelial cells in vitro"

11:30-11:50 am  Chiara Pecorini (Milan, Italy)

"Lactoferrin is localized at the two sides of the mouse mammary epithelium"

11:50-12:10 pm  Fiona O'Halloran (Fermoy, Cork, Ireland)

"Molecular and functional investigation of lactoferrin variants isolated from different cattle breeds"

12:10-12:30 pm  Ivan Sheiko (Zhodino, Belarus)

"Production of transgenic goats with human lactoferrin"

Chair Persons : E. Baker – B. Lönnerdal

3:00-3:20 pm   Ashoka Sreedhara (Aas, Norway)

"Changes in the contents of goat milk lactoferrin and lactoperoxidase in relation to the genetic variants of alpha s1-casein"

3:20-3:40 pm   Hélène Soyeurt (Gembloux, Belgium)

"Variability of lactoferrin content predicted by mid-infrared spectrometry in bovine milk"

Chair Persons : C. Teng – D. Legrand

3:50-4:20 pm    Bo Lönnerdal (Davis, TX, USA)

"Receptor-mediated endocytosis of lactoferrin "

4:20-4:40 pm    Maryam Amini (London, England, UK)

"A study of human lactoferrin and transferrin interactions with their respective bacterial receptors, LbpA and TbpA, from Neisseria meningitidis"

4:40-5:00 pm   Anthony Schryvers (Calgary, Alberta, Canada)

"Lactoferrin binding protein B mediates resistance to the antimicrobial activity of lactoferricin"

Chair Persons : J. Cornish – D. Legrand

5:30-6:00 pm    Jeremy Brock (Glasgow, Scotland, UK)

"Lactoferrin in immunity and inflammation - an overview"

6:00-6:20 pm    Sandra Gessani (Rome, Italy)

"Immunomodulatory effects of bovine lactoferrin in human myeloid dendritic cells"

6:20-6:40 pm    Shen-An Hwang (Houston, TX, USA)

"Lactoferrin enhances the BCG vaccine by promoting T-cell activation through modulation of dendritic cell presentation molecules"

6:40-7:00 pm    Koji Yamauchi (Zama, Japan)

"Hepatoprotective effect of oral bovine lactoferrin on D-galactosamine-induced hepatitis in mice: comparison with other whey proteins"

7:00-7:20 pm    Saori Kobayashi (Iwate, Japan)

"Oral therapy with bovine lactoferrin in dogs with congenital neutrophil dysfunction"

Chair Persons : J. Brock – A. Pierce

9:00-9:30 am    Sang-Yun Choi (Seoul, Korea)

"Regulation of cell proliferation and apoptosis by human lactoferrin"

9:30-9:50 am    Christophe Mariller (Villeneuve d'Ascq, France)

"Delta-lactoferrin is a transcription factor regulating cell progression and survival"

9:50-10:10 am   Stefan Imreh (Stockholm, Sweden)

"Lactoferrin: one of the tumor suppressor genes at 3p21.3"

10:10-10:30 am  Thorgunnur Petursdottir (Reykjavik, Iceland)

"Loss of the lactotransferrin gene is frequent in human solid tumors and the A29T polymorphism is common in lung cancer patients"

Chair Persons : J. Brock – A. Pierce

11:00-11:30 am  Hiroyuki Tsuda (Nagoya, Japan)

"Cancer prevention by bovine lactoferrin – From animal studies to human trials"

11:30-11:50 am  Anca Roseanu (Bucharest, Roumania)

"Effect of free and liposome-entrapped lactoferrin on murine and human melanoma cells"

11:50-12:10 pm  David Alexander (Nagoya, Japan)

"A lactoferrin expressing, helper adenovirus-dependent  vector: construction and initial observations"

Chair Persons : S. Choi - K. Shimazaki

3:00-3:30 pm    Jillian Cornish (Auckland, New Zealand)

"Lactoferrin, a regulator of bone growth"

3:30-3:50 pm    Anne Blais (Paris, France)

"Dietary bovine lactoferrin improves the bone status of ovariectomized mice"

3:50-4:10 pm    Yoshiharu Takayama (Tsukuba, Japan)

"Modulated release of bovine lactoferrin from collagen membrane and application for bone tissue engineering"

4:10-4:30 pm    Ushasree Pattamatta (Sydney, Australia)

"Bovine lactoferrin stimulates human corneal epithelial wound healing in vitro"

4:30-4:50 pm   Yasushi Suzuki (Kashiwara, Japan)

"Bovine lactoferrin promotes wound healing in diabetic mice"

Chair Persons : D. Fine - A. Schryvers

5:20-5:50 pm    Kei-ichi Shimazaki (Sapporo, Japan)

"Offensive and defensive activities of lactoferrin against microorganisms"

5:50-6:10 pm    Mark Willcox (Sydney, Australia)

"Lactoferrin acts in conjunction with other antimicrobials and controls growth of Staphylococcus epidermidis"

6:10-6:30 pm    Franscesca Berlutti (Avellino, Italy)

"Could lactoferrin be useful to counteract Burkholderia cenocepacia lung infection in cystic fibrosis patients ?"

6:30-6:50 pm    Hiroyuki Wakabayashi (Zama, Japan)

"Antimicrobial activity of lactoferrin against periodontal pathogens and its application to periodontitis patients"

8:00-10:00 pm    Wine and Cheese Party - Poster Sessions

Chair Persons : P. Valenti - H. Vogel

9:00-9:30 am    Hans Vogel (Calgary, Alberta, Canada)

"Lactoferrin, bioactive host-defense peptides and their interactions"

9:30-9:50 am    Masako Umeyama (Yokohama, Japan)

"Interaction of bovine lactoferricin with acidic phospholipid bilayers and elucidation of its antimicrobial activity as studied by solid-state NMR spectroscopy"

9:50-10:10 am   Marjolaine Arseneault (Laval, Québec, Canada)

"Interaction of Lactoferricin B with membranes: a physico-chemical approach"

10:10-10:30 am  Jan Bolscher (Amsterdam, The Netherlands)

"Chimerization of the two bovine lactoferrin peptides, lactoferricin and lactoferrampin, strongly potentiates their antimicrobial activity: biological and biophysical implications"

Chair Persons : P. Valenti - H. Vogel

11:00-11:30 am   Jian-Hua Wang (Beijing, China)

"Design and heterologous expression of novel lactoferrin derived-peptides with anti-microbial activity"

11:30-11:50 am   Anne Van Der Does (Leiden, The Netherlands)

"The antimicrobial peptide hLF1-11 enhances recognition and elimination of pathogens by macrophages"

11:50-12:10 pm   Nidia Leon-Sicairios (Culiacan, Mexico)

"Bactericidal activity of bovine lactoferrin, LFampin, LFcin and Chimeric peptide (LFcin-LFampin) against Vibrio parahaemolyticus"

Sponsor Meeting - Jean-Paul Perraudin (Les Isnes, Belgium)

Chair Persons : J.-P. Perraudin - H. Tsuda

9:00-9:30 am    Mamoru Tomita (Japan)

"Overview of recent advances of bovine lactoferrin researches for applications"

9:30-9:50 am    Piera Valenti (Rome, Italy)

"Oral administration of lactoferrin in thrombophilic pregnant women suffering of iron deficiency and iron deficiency anaemia"

9:50-10:10 am   Maki Sawada (Tokyo, Japan)

"Recombinant human lactoferrin suppresses premature cervical ripening"

10:10-10:30 am  Theresa Ochoa (Lima, Peru)

"Randomized controlled pilot study of bovine lactoferrin for prevention of diarrhea in children"

Chair Persons : J.-P. Perraudin - H. Tsuda

11:00-11:20 am  Elena Nemtsova (Moscow, Russia)

"Laprot - a unique detoxifying and anti-inflammatory preparation"

11:20-11:40 am  Daniel Fine (Newark, NJ, USA)

"The identification of a Lactoferrin polymorphism associated with caries resistance"

11:40-12:00 pm  Saichiro Yokoyama (Kagoshima, Japan)

"Responses in branchial heat shock protein 70 of scorpion fish Sebastiscus marmoratus fed dietary bovine lactoferrin"

12:00-12:20 pm  Karrie Sanders (Geelong, Australia)

"A randomised clinical trial investigating lactoferrin supplements on health parameters of chronic diseases"

12:20-12:40 pm  Louis Istasse (Liège, Belgium)

"Lactoferrin and lactoperoxidase system as oral supplements to newborn dairy calves"